Benchmarking the Quality Practices of Global Pharmaceutical Manufacturing to Advance Supply Chain Resilience
| Item Type | Journal paper |
| Abstract | Over the past several decades, pharmaceutical manufacturing has become increasingly global and supply chains have become longer, more complex, and fragmented. While pharmaceutical products available to patients and customers typically conform with appropriate standards, supply chains are often affected by disruptive events and shocks that impact public health. One approach to assuring the availability of quality pharmaceutical products is to encourage drug manufacturers to invest in quality management maturity (QMM) and promote continual improvement. The interests of patients are served by risk-based drug shortage prevention and mitigation activities that help to proactively manage supply chain complexities and ensure availability of drugs. This paper demonstrates that adherence to certain quality practices enables improved manufacturing performance. Prior research has identified quality practices that are correlated with manufacturing performance. To better understand how these quality practices can be characterized, measured, and analyzed, this research project conducted a voluntary global study of pharmaceutical manufacturing establishments. Over 200 global pharmaceutical manufacturing establishments participated in this Quality Benchmarking Study (QBS) and provided data on manufacturing performance and self-assessments of adherence to quality practices. The analysis of these data found that the implementation level for selected quality management practices correlates positively with certain Key Performance Indicators (KPIs). More specifically, we found a significant positive correlation between (i) Delivery Performance and (ii) Application of QMM principles associated with Technical Production. |
| Authors | Fellows, Matt; Friedli, Thomas; Li, Ye; Maguire, Jennifer; Rakala, Nandini; Ritz, Marten; Bernasconi, Matteo; Seiss, Mark; Stiber, Neil; Swatek, Mat & Viehmann, Alex |
| Journal or Publication Title | AAPS Journal |
| Language | English |
| Subjects | business studies health sciences |
| HSG Classification | contribution to practical use / society |
| HSG Profile Area | SoM - Business Innovation |
| Refereed | Yes |
| Date | 2022 |
| Publisher | Springer |
| Volume | 24 |
| Number | 6 |
| Number of Pages | 11 |
| ISSN-Digital | 1550-7416 |
| Publisher DOI | https://doi.org/10.1208/s12248-022-00761-7 |
| Official URL | https://rdcu.be/cXY2A |
| Depositing User | M.A. HSG Matteo Bernasconi |
| Date Deposited | 21 Oct 2022 09:03 |
| Last Modified | 25 Oct 2022 07:20 |
| URI: | https://www.alexandria.unisg.ch/publications/267654 |
DownloadFull text not available from this repository.CitationFellows, Matt; Friedli, Thomas; Li, Ye; Maguire, Jennifer; Rakala, Nandini; Ritz, Marten; Bernasconi, Matteo; Seiss, Mark; Stiber, Neil; Swatek, Mat & Viehmann, Alex (2022) Benchmarking the Quality Practices of Global Pharmaceutical Manufacturing to Advance Supply Chain Resilience. AAPS Journal, 24 (6). Statisticshttps://www.alexandria.unisg.ch/id/eprint/267654
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