To achieve long-term business success, purpose for associates, and acceptance in today’s societies, business leaders must keep a close eye on social and environmental dimensions in addition to the prerequisite of attaining adequate profits. This is especially true during times of major technological transformations. A fascinating breakthrough technology pushing such a transformation is artificial intelligence (AI). AI has great potential to make devices intelligent in the Internet of Things (IoT)—referred to as AIoT. In this chapter, we evaluate how a sustainable AIoT supports the three interrelated dimensions of profit, people, and planet.