Victoria Brügger

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Brügger
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Victoria
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victoria.bruegger@unisg.ch

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    Item type:Publication,
    Early health technology assessment of digital diabetes screening in Switzerland: cost-effectiveness and budget impact analyses
    (2026-02-11)
    Wasu Mekniran  
    ;
    Victoria Brügger  
    ;
    Magdalena Fuchs
    ;
    Qiuhan Jin
    ;
    Benjamin Wirth
    Objectives Digital biomarkers offer scalable screening for type 2 diabetes, yet adoption is stalled by uncertainty regarding economic viability. This study evaluates the cost-effectiveness and budget impact of digital screening compared to opportunistic screening from a Swiss payer perspective. Methods A probabilistic Markov cohort model was developed to simulate at-risk Swiss adults (age ≥45, BMI ≥25 kg/m²) over a 40-year horizon. The model incorporates a digital attrition parameter, inputs derived from Swiss-specific sources (e.g., the CoLaus study and FSO life tables), and statutory tariffs. Costs and outcomes were discounted at 3.0%. Results In the deterministic base-case, digital screening yielded an incremental cost-effectiveness ratio of CHF 2,912 per quality-adjusted life-year gained. Probabilistic sensitivity analysis indicated a 93.2% probability of cost-effectiveness at the CHF 50,000 threshold. The budget impact analysis estimated a Year 1 gross investment budget of CHF 27 million to identify prevalent cases, followed by long-term savings from averted complications. Conclusions Digital screening can be highly cost-effective in Switzerland. While the required Year 1 gross investment poses a liquidity challenge, reimbursement via pathway-oriented models under the Swiss tariff could align incentives with long-term complication avoidance.
    Type:journal article
    Journal:MedRxiv
    URL:https://www.medrxiv.org/content/10.64898/2026.02.10.26345992v1
    DOI:10.64898/2026.02.10.26345992
    URI:https://www.alexandria.unisg.ch/handle/20.500.14171/125108